Members
Team Leaders
Pr. Salomon MANIER
PERSTIM Lab header | PU-PH, MD PhD
Dr. Suman MITRA
Principal Investigator & team leader, PERSTIM Lab
Inserm U1366 | University of Lille | CHU de Lille
Institut Pasteur de Lille
ORCID: https://orcid.org/0000-0002-3426-371X
https://themitralab.github.io/
suman.mitrainserm.fr
+33 (0)3 20 96 52 41
Lab Management
Charlyne GARD (She/Her)
Lab Manager / Biology Engineer
ORCID: https://orcid.org/0009-0004-1608-0110
Research interests: Molecular Biology, Genomics, Transcriptomics, NGS, Single-cell approaches
Research group: Salomon MANIER
Principal Investigators
Dr Carine BRINSTER
Associate Professor, Lille University, phD
✉️ carine.brinsteruniv-lille.fr
ORCID: https://orcid.org/00000-0002-4104-7732
Research interests: Acute myeloid leukemia, T lymphocytes, mice models, minimal residual disease
Research group: Investigating the mechanisms underlying T-cell deficiency in acute myeloid leukemia and the role of the immune response in leukemic persistence.
Pr Claude PREUDHOMME
PU-PH, MD PhD
ORCID: 0000-0002-1267-9546
Fabrice SONCIN
Inserm Research Director
ORCID: https://orcid.org/0000-0001-6312-0673
Research interests: Blood vessels, vascularization, cancer, organs-on-chip, microfabrication, microfluidics, therapies
Research group: We design 3D models of blood vessels-on-chip to study the effects of anti-cancer therapies on the vascular barrier structure and functions.
Pr Jérôme KLUZA
PR, UL PhD
ORCID: 0000-0002-7346-1305
Dr. Nicolas DUPLOYEZ
MCU-PH Institut d’Hématologie Centre de Biologie-Pathologie, CHU de Lille, HDR
✉️ nicolas.duployezuniv-lille.fr
ORCID: https://orcid.org/0000-0002-3927-1022
Research interests
acute myeloid leukemia, genomics, transcriptomics, measurable residual disease
Research group
Axis 1: Unraveling the role of molecular plasticity in cancer cells persistence.
Dr. Nicolas GERMAIN
Associate Professor of Cell Biology & Clinical Biologist (MCU-PH)
ORCID: https://orcid.org/0000-0003-0867-3245
Research interests: 3D bioprinting, myeloid sarcoma, tumor microenvironment, adipocytes, leukemia, tissue engineering, drug resistance, translational models
Research group: 3D bioprinting and microenvironmental determinants of myeloid malignancies
Pr. Philippe MARCHETTI
PUPH Cell Biology, head of Lille Tissue Bank
✉️ philippe.marchetti@inserm.fr
ORCID: https://orcid.org/0000-0002-4663-6800
Research interests: 3D bioprinting, cancer metabolism, tissue engineering, adipose microenvironment
Research group: Bioengineering and tumor microenvironment axes.
Dr. Yasmine TOUIL
Research Engineer HC /PhD, HDR
ORCID: https://orcid.org/0000-0002-2286-960X
Research interests:
Immune synapse, Immune evasion, Hematological malignancies, Calcium signaling, Stem cells, Microfluidic
Research group:
Decoding Immune Synapse Alterations in Hematological Malignancies at Single-Cell Resolution.
Engineers & Technicians
Aurélie GUILLEMETTE
Assistant engineer
✉️ aurelie.guillemetteinserm.fr
ORCID: https://orcid.org/0000-0002-3422-3689
Research interests: calcium signaling, immunological synapse, single cell, microfluidic & calcium imagery
Research group: Yasmine TOUIL Team | Deciphering the interaction between immune system and tumoral cells at single cell level.
Aya ELMESAOUDI
Bioinformatics engineer CHU
Research Group: Pr. Salomon MANIER
Elise BURET
Research Engineer
Research Interests: Myeloid sarcoma, 3D modeling, cancer metabolism
Research group: Pr. Philippe MARCHETTI
Emilie LAURENGE
IE CDD CHU
Research Group: Pr. Salomon MANIER
Eva GEZ
Engineer (IE)
ORCID: https://orcid.org/0009-0008-8518-3868
Research interests: Acute myeloid leukemia, acidic extracellular pH, calcium signaling, ion channels.
Research group: Dr. Yasmine Touil’s team.
Noémie CARLIER
TR CHU
Sidonie GRIFFARD
Tech CDD CHU
William LAINE
Tech UL
ORCID: 0009-0002-2101-5124
Students
Adeline COZZANI
PhD student
ORCID: 0000-0001-5837-0459
Dr Benjamin SEGAIN
PharmD, PhD Student
ORCID: https://orcid.org/0009-0009-2885-9531
Research Interest: Understand and improve CAR-T cells under acidic conditions
Research group: Suman Mitra group
Benjamin PODVIN
PharmD, PhD student
ORCID: Benjamin Podvin (0000-0002-0616-8694) - ORCID
Research interest: hematology, multiple myeloma, genomic, NGS, BCMA, biomarker
Research group: Pr. Salomon Manier / Pr. Claude Preudhomme
Dr. Paul CHAUVET
Hematologist | PhD position
ORCID: https://orcid.org/0000-0001-6326-9283
Research interests: CAR-T cell engineering, hematological malignancies
Research group: Dr. Suman MITRA
Ibtihal HEZILI
PhD student
Research Group: Fabrice SONCIN
Dr Melinda DANTEC
PhD student
Researchers
Dr Alice MARCEAU
PH, MD
ORCID: 0000-0002-3197-0785
Pr Bruno QUESNEL
PU-PH, MD PhD
ORCID: 0000-0002-6563-2709
Pr Catherine ROCHE-LESTIENNES
PU-PH, MD PhD
ORCID: 0000-0002-7998-3817
Dr Céline BERTHON
PH, MD PhD
ORCID: 0000-0002-3474-2577
Dr. Christine DECANTER
PH CHU
ORCID: 0000-0002-8232-3959
Dr Christophe ROUMIER
PH, MD
ORCID: 0000-0002-8644-1354
Dr. Doriane CAVALIERI
PH CHU
Dr Gauthier DECOOL
PH CHU
ORCID: 0000-0003-3379-1083
Dr. Gemma BOGARD
PhD, Post-doctoral researcher
ORCID: https://orcid.org/0000-0002-1399-8709
Research interests: Tumor microenvironment, cytokine engineering, immunity, flow cytometry
Research group: Dr Suman MITRA
Dr. Lama HASAN BOU ISSA
Posdoctoral Researcher
✉️lama.hasan-bou-issainserm.fr
Research interests: Multiple myeloma, IRF4, genomic dependencies, translational oncology
Research group: Pr. Salomon Manier
Dr. Laure GOURSAUD
PH CHU
ORCID: 0000-0003-1915-9639
Dr. Laurène FENWARTH
MD, PhD, Praticien Hospialier, Institut d’Hématologie Centre de Biologie-Pathologie, CHU de LILLE
✉️ laurene.fenwarthchu-lille.fr
ORCID: https://orcid.org/0000-0003-2808-4843
Research interests: Acute myeloid leukemia, genomics, measurable residual disease, germline predisposition
Research group: Prof S. Manier | Axis 1: Unraveling the role of molecular plasticity in cancer cells persistence.
Dr. Léa FLECHON
Bioinformatics Engineer CHU
ORCID: 0000-0003-4140-475X
Research Group: Pr. Salomon MANIER
Dr Leila MOHAMMADNEZHAD
Postdoctoral Researcher
✉️ leila.mohammadnezhadinserm.fr
ORCID: https://orcid.org/0009-0001-0081-5205
Research interests: Lymphoma, DLBCL, Biomarkers, Immunology, Bioinformatics
Research group: Dr Suman Mitra
Mojtaba SHEKARKAR AZGOMI
PostDoc Researcher
ORCID: https://orcid.org/0000-0002-0642-0431
Research interests: Antigen-specific T-cell immunity, peptide-based vaccine design, immunopeptidomics, scMulti-omic analysis
Research group: Salomon MANIER
Dr Morgane NUDEL ORTMANS
PH, MD
ORCID: 0000-0001-9100-2316
Dr. Nicolas TOUYA
Post-doctoral fellow
ORCID: 0000-0003-0140-6371
Dr Olivier NIBOUREL
PH, MD
ORCID: 0000-0003-1909-306X
Dr. Romane JOUDINAUD
AHU CHU
ORCID: 0000-0001-8451-0873
Dr. Sandrine GEFFROY
IR CHU
ORCID: 0000-0002-8103-029X
Sofia TITAH
Post-doctoral Researcher
ORCID: https://orcid.org/0000-0003-4892-6817
Research interests: acute myeloid leukemia ; immunological synapse ; calcium signaling ; microfluidic.
Research group: Dr. Yasmine Touil Research Group
Pr Stéphanie POULAIN
PU-PH, PharmD PhD
ORCID: 0000-0002-1792-7270
Dr. Victoria CACHEUX
PH CHU
Dr Yasmin RIDA
Postdoctoral researcher
Research interests: Organ-on-chip, blood vessels, liver.
Research group: Vaisseaux, Fabrice SONCIN