Software & Tools

Precision Oncology

  • GBM-cRegMap (web server): A co-regulatory influence map of  glioblastoma  heterogeneity and evolution – From cells in vitro to tumors and back again.
  • BLCA-cRegMap (web server): A co-regulatory influence map of  bladder cancer  heterogeneity and evolution – From cells in vitro to tumors and back again.
  • BRCA-cRegMap (web server): A co-regulatory influence map of  breast cancer  heterogeneity and evolution – From cells in vitro to tumors and back again.
  • PDAC-cRegMap (web server): A co-regulatory influence map of  pancreatic cancer  heterogeneity and evolution – From cells in vitro to tumors and back again.

Computational Biology

  • H-Licorn: learning cooperative gene regulatory networks from transcriptome data
  • CoRegNet: is an R bioconductor package, which enables infers master regulators controlling the transition between phenotypes. 
  • CoRegFlux: R Bioconductor package. Integrating transcriptional activity in genome-scale models of metabolism.
  • LatNet: R package. Latent network-based representations for large-scale gene expression data analysis.
  • PEPPER: is a plugin cytoscape, which enables finding pathways connecting a protein set within a PPI-network using multi-objective optimization. 

Machine Learning

  • WRFO (python package) : Weighted Random Forest Optimization
  • GLOW (python package): Learning Global-Local Multi-Scale Node Embeddings with Random Walks and Landmark-Guided Optimization
  • SkyClust (Java): Clustering attributed graph using multi-objective optimization.